No association between in utero exposure to emissions from a coalmine fire and post-natal lung function.

ABSTRACT:

Background and objective

Studies linking early life exposure to air pollution and subsequent impaired lung health have focused on chronic, low-level exposures in urban settings. We aimed to determine whether in utero exposure to an acute, high-intensity air pollution episode impaired lung function 7-years later.

Method

We conducted a prospective cohort study of children who lived in the vicinity of a coalmine fire. Respiratory function was measured using the forced oscillation technique (FOT). Z-scores for resistance at 5 Hz (R₅), reactance at 5 Hz (X₅) and area under the reactance curve (AX) were calculated. Two sets of analyses were conducted to address two separate questions: (1) whether mine fire exposure (a binary indicator; conceived after the min

SUBMITTER: Hemstock EJ 

PROVIDER: S-EPMC10103534 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature