Evolution of cross-frequency coupling between endogenous oscillations over the temporal cortex in very premature neonates.

ABSTRACT: Temporal theta activity in coalescence with slow-wave (TTA-SW) is one of the first neurobiomarkers of the neurodevelopment of perisylvian networks in the electroencephalography (EEG). Dynamic changes in the microstructure and activity within neural networks are reflected in the EEG. Slow oscillation slope can reflect synaptic strength, and cross-frequency coupling (CFC), associated with several putative functions in adults, can reflect neural communication. Here, we investigated the evolution of CFC, in terms of SW theta phase-amplitude coupling (PAC), during the course of very early development between 25 and 32 weeks of gestational age in 23 premature neonates. We used high-resolution EEG and dipole models as spatial filters to extract the source waveforms corresponding to TTA-SW. We als

SUBMITTER: Saadatmehr B 

PROVIDER: S-EPMC10103643 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature