Correlated signatures of social behavior in cerebellum and anterior cingulate cortex.

ABSTRACT: The cerebellum has been implicated in the regulation of social behavior. Its influence is thought to arise from communication, via the thalamus, to forebrain regions integral in the expression of social interactions, including the anterior cingulate cortex (ACC). However, the signals encoded or the nature of the communication between the cerebellum and these brain regions is poorly understood. Here, we describe an approach that overcomes technical challenges in exploring the coordination of distant brain regions at high temporal and spatial resolution during social behavior. We developed the E-Scope, an electrophysiology-integrated miniature microscope, to synchronously measure extracellular electrical activity in the cerebellum along with calcium imaging of the ACC. This single coaxial ca

SUBMITTER: Hur SW 

PROVIDER: S-EPMC10104017 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature