Expert Consensus on the Use of On-Demand Treatments for OFF Episodes in Parkinson's Disease: A Modified Delphi Panel.

ABSTRACT:

Background

On-demand treatments can treat OFF episodes in Parkinson's disease, however, there is limited information regarding when to prescribe them.

Objective

Develop expert consensus to determine appropriate clinical factors for considering on-demand treatments.

Methods

Using a RAND/UCLA modified Delphi panel method, a panel developed consensus on the use of on-demand treatments for OFF episodes.

Results

The panel agreed on-demand treatments were appropriate when OFF episodes were associated with greater functional impact and interfered with basic daily activities. The panel also agreed on-demand treatment may be appropriate for patients with morning akinesia and/or delayed ON of first levodopa dose and >1 type of OFF episode (eg, early morning OFF or wearin

SUBMITTER: Isaacson SH 

PROVIDER: S-EPMC10105118 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature