Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study.

ABSTRACT:

Background

The UK government reclassified gabapentin and pregabalin as 'controlled drugs' from April 2019. This study aimed to describe the trends in gabapentinoid prescribing before and immediately after reclassification, in the UK Clinical Practice Research Datalink, an electronic primary care health record broadly representative of the UK.

Methods

Separately for gabapentin and pregabalin, we calculated annual incident and prevalent prescribing rates from year of UK approval (April 1997 and 2004 respectively) to September 2019, and monthly incident and prevalent prescribing rates (October 2017-September 2019). Significant changes in temporal trends were determined using joinpoint regression. We also described potential prescribing indications, prior pain-related prescribin

SUBMITTER: Ashworth J 

PROVIDER: S-EPMC10105252 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature