Advanced Therapy Medicinal Products in Vitiligo; Current Status, Future Prospect, and Approved Treatments.

ABSTRACT: Vitiligo is an auto-immune disease, causing depigmentation of skin in 0.2-1.8% of global population. Topical corticosteroids and calcineurin inhibitors are the only treatments with firm evidence of optimal effectiveness with considerable side effects. Phototherapies might not induce serious side effects, although the effectiveness of the method is limited. Advanced therapy medicinal products (ATMPs) are emerging treatment modalities based on correction and replacement of affected genes, damaged tissues or cells in treatment of difficult-to-treat diseases. Due to optimal effectiveness and minimal side effects, ATMPs have recently gained much attention in order to develop new treatments. In this review, the ATMPs for treating vitiligo were along with its clinical success, affordability and c

SUBMITTER: Ghashghaei S 

PROVIDER: S-EPMC10105300 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature