Serum neurofilament light chain as a predictive marker of neurologic outcome after cardiac arrest: a meta-analysis.

ABSTRACT:

Objective

Recently, an increasing number of studies have suggested using serum neurofilament light (NfL) chain to predict the neurologic outcome after cardiac arrest. However, the predictive ability of this approach remains inconclusive. Meta-analysis was performed on related studies to assess the ability of serum NfL to predict the neurologic outcome after cardiac arrest.

Materials and methods

PubMed, ScienceDirect and Embase were systematically searched from the date of their inception until June 2022. Data were extracted to calculate the area under the receiver operating characteristic curve (AUC), the sensitivity, the specificity and the publication bias to evaluate the predictive power of serum NfL using Stata 14.0.

Results

Nine studies were included in the prese

SUBMITTER: Wang SL 

PROVIDER: S-EPMC10105388 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature