A beginner's guide on the use of brain organoids for neuroscientists: a systematic review.

ABSTRACT: The first human brain organoid protocol was presented in the beginning of the previous decade, and since then, the field witnessed the development of many new brain region-specific models, and subsequent protocol adaptations and modifications. The vast amount of data available on brain organoid technology may be overwhelming for scientists new to the field and consequently decrease its accessibility. Here, we aimed at providing a practical guide for new researchers in the field by systematically reviewing human brain organoid publications. Articles published between 2010 and 2020 were selected and categorised for brain organoid applications. Those describing neurodevelopmental studies or protocols for novel organoid models were further analysed for culture duration of the brain organoids,

SUBMITTER: Mulder LA 

PROVIDER: S-EPMC10105545 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature