High circulating fibroblast growth factor-21 levels as a screening marker in fatty pancreas patients.

ABSTRACT:

Background

The study aimed to detect the serum levels of fibroblast growth factor-21 (FGF-21) in fatty pancreas (FP) patients and to investigate their potential clinical value.

Methods

We screened patients with FP using transabdominal ultrasound. The anthropometric, biochemical and serum levels of FGF-21 were compared between the FP group and the normal control (NC) group. A receiver operating characteristic (ROC) curve was used to evaluate the predictive value of serum FGF-21 for FP patients.

Results

Compared with the NC group, body mass index, fasting blood glucose levels, uric acid levels and cholesterol levels of the FP group were significantly higher, while the high-density lipoprotein level was lower. In addition, levels of serum FGF-21, resistin, leptin and tum

SUBMITTER: Han F 

PROVIDER: S-EPMC10105565 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature