Cohort profile: SUPER-Finland - the Finnish study for hereditary mechanisms of psychotic disorders.

ABSTRACT:

Purpose

SUPER-Finland is a large Finnish collection of psychosis cases. This cohort also represents the Finnish contribution to the Stanley Global Neuropsychiatric Genetics Initiative, which seeks to diversify genetic sample collection to include Asian, Latin American and African populations in addition to known population isolates, such as Finland.

Participants

10 474 individuals aged 18 years or older were recruited throughout the country. The subjects have been genotyped with a genome-wide genotyping chip and exome sequenced. A subset of 897 individuals selected from known population sub-isolates were selected for whole-genome sequencing. Recruitment was done between November 2015 and December 2018.

Findings to date

5757 (55.2%) had a diagnosis of schizophrenia, 94

SUBMITTER: Lahteenvuo M 

PROVIDER: S-EPMC10106053 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature