Primary series COVID-19 vaccine effectiveness among healthcare workers in Albania, February-December 2021.

ABSTRACT:

Background

Healthcare workers have experienced high rates of morbidity and mortality from coronavirus disease 2019 (COVID-19).

Methods

A prospective cohort study was conducted in three Albanian hospitals between 19 February and 14 December 2021. All participants underwent polymerase chain reaction (PCR) and serological testing at enrolment, regular serology throughout, and PCR testing when symptomatic.Vaccine effectiveness (VE) against COVID-19 and against all severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections (symptomatic or asymptomatic) was estimated. VE was estimated using a Cox regression model, with vaccination status as a time-varying variable.

Findings

In total, 1504 HCWs were enrolled in this study; 70% had evidence of prior SARS-CoV-2 in

SUBMITTER: Rubin-Smith JE 

PROVIDER: S-EPMC10106115 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature