High cut-off membranes in patients requiring renal replacement therapy: a systematic review and meta-analysis.

ABSTRACT:

Background

Whether high cut-off (HCO) membranes are more effective than high-flux (HF) membranes in patients requiring renal replacement therapy (RRT) remains controversial. The aim of this systematic review was to investigate the efficacy of HCO membranes regarding the clearance of inflammation-related mediators, β2-microglobulin and urea; albumin loss; and all-cause mortality in patients requiring RRT.

Methods

We searched all relevant studies on PubMed, Embase, Web of Science, the Cochrane Library, and China National Knowledge Infrastructure, with no language or publication year restrictions. Two reviewers independently selected studies and extracted data using a prespecified extraction instrument. Only randomized controlled trials (RCTs) were included. Summary estimates o

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC10106154 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature