Essential tremor-Parkinson's disease syndrome: clinical characteristics and subtypes using cluster analysis.

ABSTRACT:

Background

Essential tremor (ET) and Parkinson's disease (PD) are common movement disorders. ET-PD syndrome is characterized by the occurrence of PD in patients with a previous history of ET, which may be an independent phenotype distinct from PD. This study aims to identify clinical characteristics and subtypes in ET-PD.

Methods

A total of 93 newly diagnosed ET-PD patients and 93 newly diagnosed PD patients matched for age, sex, education, and disease duration of PD were selected using propensity score matching analysis. The K-means cluster analysis was performed for 11 variables derived from the ET-PD group, and cluster profiles were established through statistical analysis of demographic and clinical variables.

Results

The ET-PD group consisted of a high number of

SUBMITTER: Hou Y 

PROVIDER: S-EPMC10106194 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature