Genomic surveillance of SARS-CoV-2 strains circulating in Iran during six waves of the pandemic.

ABSTRACT:

Background

SARS-CoV-2 genomic surveillance is necessary for the detection, monitoring, and evaluation of virus variants, which can have increased transmissibility, disease severity, or other adverse effects. We sequenced 330 SARS-CoV-2 genomes during the sixth wave of the COVID pandemic in Iran and compared them with five previous waves, for identifying SARS-CoV-2 variants, the genomic behavior of the virus, and understanding its characteristics.

Methods

After viral RNA extraction from clinical samples collected during the COVID-19 pandemic, next generation sequencing was performed using the Nextseq and Nanopore platforms. The sequencing data were analyzed and compared with reference sequences.

Results

In Iran during the first wave, V and L clades were detected. The s

SUBMITTER: Sadeghi K 

PROVIDER: S-EPMC10106497 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature