Nasal swab as an alternative specimen for the detection of severe acute respiratory syndrome coronavirus 2.

ABSTRACT:

Background and aims

The coronavirus disease 2019 (COVID-19) has brought serious threats to public health worldwide. Nasopharyngeal, nasal swabs, and saliva specimens are used to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, limited data are available on the performance of less invasive nasal swab for testing COVID-19. This study aimed to compare the diagnostic performance of nasal swabs with nasopharyngeal swabs using real-time reverse transcription polymerase chain reaction (RT-PCR) considering viral load, onset of symptoms, and disease severity.

Methods

A total of 449 suspected COVIDCOVID-19 individuals were recruited. Both nasopharyngeal and nasal swabs were collected from the same individual. Viral RNA was extracted and tested by real-time

SUBMITTER: Nahar K 

PROVIDER: S-EPMC10106929 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature