Pesticide Prioritization by Potential Biological Effects in Tributaries of the Laurentian Great Lakes.

ABSTRACT: Watersheds of the Great Lakes Basin (USA/Canada) are highly modified and impacted by human activities including pesticide use. Despite labeling restrictions intended to minimize risks to nontarget organisms, concerns remain that environmental exposures to pesticides may be occurring at levels negatively impacting nontarget organisms. We used a combination of organismal-level toxicity estimates (in vivo aquatic life benchmarks) and data from high-throughput screening (HTS) assays (in vitro benchmarks) to prioritize pesticides and sites of concern in streams at 16 tributaries to the Great Lakes Basin. In vivo or in vitro benchmark values were exceeded at 15 sites, 10 of which had exceedances throughout the year. Pesticides had the greatest potential biological impact at the site with the gre

SUBMITTER: Oliver SK 

PROVIDER: S-EPMC10107260 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature