GLIM-defined malnutrition and overall survival in cancer patients: A meta-analysis.

ABSTRACT:

Background

Malnutrition defined by the Global Leadership Initiative on Malnutrition (GLIM) has been associated with cancer mortality, but the effect is limited and inconsistent. We performed this meta-analysis aiming to assess this relationship in patients with cancer.

Methods

We systematically searched Embase, PubMed, Web of Science, Cochrane, CINAHL, CNKI, Wanfang, and VIP databases from January 1, 2019, to July 1, 2022. Studies evaluating the prognostic effect of GLIM-defined malnutrition on cancer survival were included. A fixed-effect model was fitted to estimate the combined hazard ratio (HR) with a 95% CI. Heterogeneity of studies was analyzed using the I² statistic. Quality assessment were performed using the Newcastle-Ottawa Scale (NOS) and the Grading of

SUBMITTER: Yin L 

PROVIDER: S-EPMC10107432 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature