Longitudinal study of clinical and neurophysiological features in essential tremor.

ABSTRACT:

Background and purpose

Essential tremor (ET) is a common and heterogeneous disorder characterized by postural/kinetic tremor of the upper limbs and other body segments and by non-motor symptoms, including cognitive and psychiatric abnormalities. Only a limited number of longitudinal studies have comprehensively and simultaneously investigated motor and non-motor symptom progression in ET. Possible soft signs that configure the ET-plus diagnosis are also under-investigated in follow-up studies. We aimed to longitudinally investigate the progression of ET manifestations by means of clinical and neurophysiological evaluation.

Methods

Thirty-seven ET patients underwent evaluation at baseline (T0) and at follow-up (T1; mean interval ± SD = 39.89 ± 9.83 months). The assessment inc

SUBMITTER: Angelini L 

PROVIDER: S-EPMC10107502 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature