The impact of preexisting psychiatric disorders and antidepressant use on COVID-19 related outcomes: a multicenter study.

ABSTRACT: Pre-existing mental disorders are linked to COVID-19-related outcomes. However, the findings are inconsistent and a thorough analysis of a broader spectrum of outcomes such as COVID-19 infection severity, morbidity, and mortality is required. We investigated whether the presence of psychiatric diagnoses and/or the use of antidepressants influenced the severity of the outcome of COVID-19. This retrospective cohort study evaluated electronic health records from the INSIGHT Clinical Research Network in 116,498 individuals who were diagnosed with COVID-19 between March 1, 2020, and February 23, 2021. We examined hospitalization, intubation/mechanical ventilation, acute kidney failure, severe sepsis, and death as COVID-19-related outcomes. After using propensity score matching to control for de

SUBMITTER: Schultebraucks K 

PROVIDER: S-EPMC10107583 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature