Challenges in Elucidating the Free Energy Scheme of the Laccase Catalyzed Reduction of Oxygen.

ABSTRACT: Artificial redox catalysts are typically limited by unfavorable scaling relations of reaction intermediates leading to a significant overpotential in multi-electron redox reactions such as for example the oxygen reduction reaction (ORR). The multicopper oxidase laccase is able to catalyze the ORR in nature. In particular the high-potential variants show a remarkably low overpotential for the ORR and apparently do not suffer from such unfavorable scaling relations. Although laccases are intensively studied, it is presently unknown why the overpotential for ORR is so low and a clear description regarding the thermodynamics of the catalytic cycle and the underlying design principles is lacking. In order to understand the laccase catalyzed ORR from an electrochemical perspective, elucidation o

SUBMITTER: den Boer D 

PROVIDER: S-EPMC10107611 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature