Semaglutide for cardiovascular event reduction in people with overweight or obesity: SELECT study baseline characteristics.

ABSTRACT:

Objective

This paper describes the baseline characteristics of the Semaglutide Effects on Heart Disease and Stroke in Patients with Overweight or Obesity (SELECT) study, one of the largest cardiovascular (CV) outcome studies in the field of obesity, which evaluates the effect of semaglutide versus placebo on major CV events.

Methods

SELECT enrolled individuals with overweight or obesity without diabetes, with prior myocardial infarction, stroke, and/or peripheral artery disease. This study reports participants' baseline characteristics in the full study population and subgroups defined by baseline glycated hemoglobin (HbA_1c ; <5.7%, ≥5.7 to <6.0%, ≥6.0 to <6.5%), baseline waist to height ratio tertile, and qualifying prior CV event or condition.

Results

The

SUBMITTER: Lingvay I 

PROVIDER: S-EPMC10107832 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature