A multivariate genetic analysis of anxiety sensitivity, environmental sensitivity and reported life events in adolescents.

ABSTRACT:

Background

Despite being considered a measure of environmental risk, reported life events are partly heritable. One mechanism that may contribute to this heritability is genetic influences on sensitivity, relating to how individuals process and interpret internal and external signals. The aim of this study was to explore the genetic and environmental overlap between self-reported life events and measures of sensitivity.

Methods

At age 17, 2,939 individuals from the Twins Early Development Study (TEDS) completed measures of anxiety sensitivity (Children's Anxiety Sensitivity Index), environmental sensitivity (Highly Sensitive Child Scale) and reported their experience of 20 recent life events. Using multivariate Cholesky decomposition models, we investigated the shared geneti

SUBMITTER: Peel AJ 

PROVIDER: S-EPMC10107936 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature