Reduced versus standard intradetrusor OnabotulinumtoxinA injections for treatment of overactive bladder.

ABSTRACT:

Background

Intradetrusor onabotulinumtoxinA injection is an effective advanced treatment for overactive bladder. While the effective dosages have been well studied, very little data exist on treatment efficacy using differing injection techniques. The objective of this study was to determine whether the efficacy of a reduced injection technique of 5 injection sites was noninferior to the standard technique of 20 injection sites of intradetrusor onabotulinumtoxinA for treatment of overactive bladder.

Methods

In this randomized noninferiority trial, men and women seeking treatment of overactive bladder with intradetrusor onabotulinumtoxinA injections were randomized to receive 100 units administered via either a reduced injection technique of 5 injection sites or a standard in

SUBMITTER: DiCarlo-Meacham AM 

PROVIDER: S-EPMC10108158 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature