Association of placental and umbilical cord characteristics with cerebral palsy: national cohort study.

ABSTRACT:

Objectives

Cerebral palsy (CP) is a group of movement disorders usually diagnosed in childhood. A substantial proportion are thought to be caused by antenatal events. Abnormalities of the umbilical cord and placenta are associated with an increased risk of adverse neonatal outcomes, but it is unclear whether these conditions also carry an increased risk of CP. We aimed to determine whether abnormalities of the umbilical cord or placenta are associated with CP and assess if these associations differ by sex of the child or gestational age at birth.

Methods

We performed a national cohort study by linking data from The Medical Birth Registry of Norway with other national registries. All liveborn singletons born between 1999 and 2017 (n = 1 087 486) were included and followed up

SUBMITTER: Ebbing C 

PROVIDER: S-EPMC10108292 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature