Non-alcoholic fatty liver disease (NAFLD) is associated with an increased incidence of chronic kidney disease (CKD).

ABSTRACT:

Background

Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in the western world. The excess mortality in NAFLD patients is strongly related to extrahepatic comorbidities. Recently, an association between NAFLD and chronic kidney disease (CKD) has been reported in various populations.

Methods

Based on the IQVIA Disease Analyzer database, this retrospective study examined two cohorts from Germany matched for sex, age, index year, annual visit frequency, hypertension, and diabetes, including 92,225 patients with and without NAFLD. The incidence of CKD was assessed as a function of NAFLD using Cox regression models.

Results

A total of 92,225 NAFLD patients as well as 92,225 patients without NAFLD were included into analyses. CKD was

SUBMITTER: Roderburg C 

PROVIDER: S-EPMC10108448 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature