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Current perspectives on cell-assisted lipotransfer for breast cancer patients after radiotherapy.


ABSTRACT:

Background

Cell-assisted lipotransfer (CAL), a technique of autologous adipose transplantation enriched with adipose-derived stem cells (ADSCs), has the potential to improve cosmetic outcomes at irradiated sites. However, many concerns have been raised about the possibility of ADSCs increasing oncological risk in cancer patients. With the increasing demand for CAL reconstruction, there is an urgent need to determine whether CAL treatment could compromise oncological safety after radiotherapy, as well as to evaluate its efficacy in guiding clinical decisions.

Methods

A PRISMA-compliant systematic review of the safety and efficacy of CAL in breast cancer patients after radiotherapy was conducted. The PubMed, Ovid, Cochrane Library, and ClinicalTrials.gov databases were compreh

SUBMITTER: Wu Q 

PROVIDER: S-EPMC10108507 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature