Association between inflammatory markers and bone mineral density: a cross-sectional study from NHANES 2007-2010.

ABSTRACT:

Purpose

Monocyte-to-lymphocyte ratio (MLR), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) are acknowledged as novel inflammatory markers. However, studies investigating the correlation between inflammatory markers and osteoporosis (OP) remain scarce. We aimed to investigate the relationship between NLR, MLR, PLR and bone mineral density (BMD).

Methods

A total of 9054 participants from the National Health and Nutrition Examination Survey were included in the study. MLR, NLR and PLR were calculated for each patient based on routine blood tests. Given the complex study design and sample weights, the relationship between inflammatory markers and BMD was evaluated through weighted multivariable-adjusted logistic regression and smooth curve fittings. In

SUBMITTER: Chen S 

PROVIDER: S-EPMC10108543 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature