Exposure to umbilical cord management approaches and death or neurodevelopmental impairment at 22-26 months' corrected age after extremely preterm birth.

ABSTRACT:

Objective

To compare death or severe neurodevelopmental impairment (NDI) at 22-26 months' corrected age (CA) among extremely preterm infants following exposure to different forms of umbilical cord management.

Design

Retrospective study.

Setting

Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network registry.

Patients

Infants born <27 weeks' gestation in 2016-2018 without severe congenital anomalies who received active treatment after birth and underwent neurodevelopmental assessments between 22 and 26 months' CA.

Exposures

Immediate cord clamping (ICC), delayed cord clamping (DCC) or umbilical cord milking (UCM).

Main outcomes and measure

Primary composite outcome of death or severe NDI at

SUBMITTER: Handley SC 

PROVIDER: S-EPMC10108713 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature