Low vitamin A levels are associated with liver-related mortality: a nationally representative cohort study.

ABSTRACT:

Introduction

Vitamin A, a fat-soluble vitamin that includes retinol and carotenoids, is implicated in liver fibrosis, whereas its deficiency has been associated with various liver diseases and higher overall mortality. This study aims to determine the relationship between levels of vitamin A species and liver fibrosis, as well as liver-related mortality in the population of the US.

Methods

A total of 12,299 participants from the National Health and Nutrition Examination Survey III (NHANES III) were analyzed to provide nationally representative estimates of the relationship between the levels of vitamin A species and liver fibrosis measured by Fibrosis-4 (FIB-4) index and liver-related mortality.

Results

A low blood level of retinol, but not other retinoid derivatives,

SUBMITTER: Song J 

PROVIDER: S-EPMC10109132 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature