Effects of 660-nm LED photobiomodulation on drebrin expression pattern and astrocyte migration.

ABSTRACT: Photobiomodulation (PBM) is a therapeutic tool that uses red or near-infrared light in medical applications. It's applications in both central (CNS) and peripheral nervous system (PNS) are widely studied. Among glial cells, astrocytes are known to be activated in injured or damaged brains. Astrocytic cell migration is crucial for maintaining homeostasis in the brain. Our previous study showed that PBM led to astrocyte proliferation and differentiation, but the effects on migration has not been investigated. The aim of this study was to evaluate the effect of PBM on astrocyte migration, drebrin (DBN) expression and cytoplasmic morphology using primary cultured rat astrocyte. We applied a 660-nm light-emitting diode (LED) with fluence of 6, 12 and 18 J/cm². PBM effects on astrocyt

SUBMITTER: Yoon SR 

PROVIDER: S-EPMC10110518 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature