Toxicological assessment of Phormidium sp. derived copper oxide nanoparticles for its biomedical and environmental applications.

ABSTRACT: Driven by the need to biosynthesized alternate biomedical agents to prevent and treat infection, copper oxide nanoparticles (CuONPs) have surfaced as a promising avenue. Cyanobacteria-derived synthesis of CuONPs is of substantive interest as it offers an eco-friendly, cost-effective, and biocompatible route. In the present study biosynthesized CuONPs were characterized and investigated regarding their toxicity. Morphological analysis using TEM, SEM and AFM showed the spherical particle size of 20.7 nm with 96% copper that confirmed the purity of CuONPs. Biogenic CuONPs with IC₅₀ value of 64.6 µg ml^-1 showed 90% scavenging of free radicals in superoxide radical scavenging assay. CuONPs showed enhanced anti-inflammatory activity by 86% of protein denaturation with IC

SUBMITTER: Asif N 

PROVIDER: S-EPMC10110551 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature