Influence of biological sex, age and smoking on Graves' orbitopathy - a ten-year tertiary referral center analysis.

ABSTRACT:

Purpose

Severity of Graves' orbitopathy (GO) shows wide individual differences. For optimal treatment, it is important to be able to predict the natural course of the disease as accurate as possible to counteract with anti-inflammatory and surgical treatment. Therefore, we aimed to further elucidate the impact of sex, age and smoking on GO.

Methods

We collected the clinical and demographic data of all patients of our tertiary referral center from January 2008 till December 2018 and analyzed it with descriptive statistics. Only patients with a complete data set were included in the further analysis. Odds ratio's for moderate-to-severe and sight-threatening GO in relation to age, sex and smoking were calculated by means of multivariate logistic regression models.

Results

SUBMITTER: Oeverhaus M 

PROVIDER: S-EPMC10110835 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature