Identification of DYNLT1 associated with proliferation, relapse, and metastasis in breast cancer.

ABSTRACT:

Background

Breast cancer (BC) is the most common malignant disease worldwide. Although the survival rate is improved in recent years, the prognosis is still bleak once recurrence and metastasis occur. It is vital to investigate more efficient biomarkers for predicting the metastasis and relapse of BC. DYNLT1 has been reported that participating in the progression of multiple cancers. However, there is still a lack of study about the correlation between DYNLT1 and BC.

Methods

In this study, we evaluated and validated the expression pattern and prognostic implication of DYNLT1 in BC with multiple public cohorts and BC tumor microarrays (TMAs) of paraffin-embedded tissues collected from the Affiliated Hospital of Jining Medical University. The response biomarkers for immune the

SUBMITTER: Miao S 

PROVIDER: S-EPMC10110886 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature