The genetic basis of adaptation to copper pollution in Drosophila melanogaster.

ABSTRACT: Introduction: Heavy metal pollutants can have long lasting negative impacts on ecosystem health and can shape the evolution of species. The persistent and ubiquitous nature of heavy metal pollution provides an opportunity to characterize the genetic mechanisms that contribute to metal resistance in natural populations. Methods: We examined variation in resistance to copper, a common heavy metal contaminant, using wild collections of the model organism Drosophila melanogaster. Flies were collected from multiple sites that varied in copper contamination risk. We characterized phenotypic variation in copper resistance within and among populations using bulked segregant analysis to identify regions of the genome that contribute to copper resistance. Results and Discussi

SUBMITTER: Everman ER 

PROVIDER: S-EPMC10110907 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature