Potential benefits of vitamin D for sepsis prophylaxis in critical ill patients.

ABSTRACT:

Background

Vitamin D deficiency is common in critically ill patients with suspected infection and is strongly associated with the predisposition of sepsis and a poor prognosis. The effectiveness of vitamin D supplementation for preventing sepsis remains unclear. This retrospective cohort study investigated the effect of vitamin D supplementation on sepsis prophylaxis in critically ill patients with suspected infection.

Methods

This retrospective cohort study included 19,816 adult patients with suspected infection in intensive care units (ICU) from 2008 to 2019 at the Beth Israel Deaconess Medical Center, Boston, USA. The included patients were divided into the vitamin D cohort or non-vitamin D cohort according to vitamin D administration status. The primary outcomes were the

SUBMITTER: Guan J 

PROVIDER: S-EPMC10110989 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature