Gut Microbiota Dysbiosis Correlates With Long COVID-19 at One-Year After Discharge.

ABSTRACT:

Background

Long coronavirus disease 2019 (COVID-19) in recovered patients (RPs) is gradually recognized by more people. However, how long it will last and the underlining mechanism remains unclear.

Methods

We conducted a prospective follow-up study to evaluate the long-term symptoms and clinical indices of RPs at one-year after discharge from Union Hospital, Wuhan, China between December 2020 to May 2021. We also performed the 16S rRNA sequencing of stool samples from RPs and healthy controls (HCs) and analyzed the correlation between the gut microbiota and long COVID-19.

Results

In total, 187 RPs were enrolled, among them, 84 (44.9%) RPs reported long COVID-19 symptoms at one-year after discharge. The most common long-term symptoms were cardiopulmonary symptoms, incl

SUBMITTER: Zhang D 

PROVIDER: S-EPMC10111044 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature