Characterization of aortic aging using 3D multi-parametric MRI-long-term follow-up in a population study.

ABSTRACT: We comprehensively studied morphological and functional aortic aging in a population study using modern three-dimensional MR imaging to allow future comparison in patients with diseases of the aortic valve or aorta. We followed 80 of 126 subjects of a population study (20 to 80 years of age at baseline) using the identical methodology 6.0 ± 0.5 years later. All underwent 3 T MRI of the thoracic aorta including 3D T1 weighted MRI (spatial resolution 1 mm³) for measuring aortic diameter and plaque thickness and 4D flow MRI (spatial/temporal resolution = 2 mm³/20 ms) for calculating global and regional aortic pulse wave velocity (PWV) and helicity of aortic blood flow. Mean diameter of the ascending aorta (AAo) decreased and plaque thickness increased significantly in th

SUBMITTER: Loose S 

PROVIDER: S-EPMC10111081 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature