Incident Atrial Fibrillation and Risk of Dementia in a Diverse, Community-Based Population.

ABSTRACT: Background Atrial fibrillation (AF) is the most common, clinically relevant arrhythmia in adults and associated with ischemic stroke and premature death. However, data are conflicting on whether AF is independently associated with risk of dementia, particularly in diverse populations. Methods and Results We identified all adults from 2 large integrated health care delivery systems between 2010 and 2017 and performed a 1:1 match of incident AF: no AF by age at index date, sex, estimated glomerular filtration rate category, and study site. Subsequent dementia was identified through previously validated diagnosis codes. Fine-Gray subdistribution hazard models were used to examine the association of incident AF (versus no AF) with risk of incident dementia, adjusting for sociodemographics and

SUBMITTER: Bansal N 

PROVIDER: S-EPMC10111519 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature