Prognostic Value of Transthoracic Echocardiography in Children With Pulmonary Arterial Hypertension.

ABSTRACT: Background Transthoracic echocardiography is part of the regular follow-up protocol at most pediatric pulmonary arterial hypertension (PAH) centers. We aimed to develop a comprehensive and simple echocardiographic risk stratification for children with PAH. Methods and Results We included 63 children with PAH and a biventricular cardiac anatomy without relevant shunt lesions (60% female patients; mean age, 9.0 years; 42 idiopathic PAH and 21 associated PAH) undergoing a standardized transthoracic echocardiographic assessment. The prognostic value of echocardiographic parameters was assessed using Cox proportional hazards survival analysis and recursive partitioning for classification tree methods. Over a median follow-up period of 4.0 years, 17 patients died and 4 underwent lung transplanta

SUBMITTER: Lammers AE 

PROVIDER: S-EPMC10111552 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature