Cutavirus on the skin in an Asian cohort: identification of a novel geographically related genotype.

ABSTRACT:

Background

Cutavirus (CuV) is the newest human parvovirus and is currently receiving increasing attention because of its possible association with cutaneous T-cell lymphoma. Despite the pathogenetic potential of CuV, it has been detected in normal skin; however, little is known about the prevalence, infection levels, and genetic variations of this virus in the skin of the general population.

Methods

We investigated the CuV DNA prevalence and viral loads concerning age, sampling location, and gender using 678 skin swabs collected from the normal-appearing skins of 339 Japanese participants aged 2-99 years. Phylogenetic analyses were also conducted based on the near-full-length CuV sequences identified in this study.

Results

Both the CuV DNA prevalence and viral loads w

SUBMITTER: Hashida Y 

PROVIDER: S-EPMC10111705 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature