Therapeutic effects of vasopressin on cardiac arrest: a systematic review and meta-analysis.

ABSTRACT:

Objective

To demonstrate the therapeutic effect of vasopressin as an alternative treatment for cardiac arrest.

Design

Systematic review and meta-analysis.

Methods

PubMed, EMBASE, the Cochrane Library and Web of Science were searched for randomised controlled trials. The intervention included administration of vasopressin alone or vasopressin combined with epinephrine or vasopressin, steroids and epinephrine (VSE) versus epinephrine combined with placebo as control group. The primary outcome was the return of spontaneous circulation (ROSC). The secondary outcomes included mid-term survival and mid-term good neurological outcome. We conducted subgroup analyses of the primary outcome based on different settings, different study drug strategies and different types of init

SUBMITTER: Yan W 

PROVIDER: S-EPMC10111914 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature