The association between mannose binding lectin gene polymorphisms and the risk of neonatal sepsis: an updated meta-analysis.

ABSTRACT:

Objectives

To evaluate the relationship between mannose-binding lectin (MBL) polymorphism and neonatal sepsis to provide ideas for early diagnosis and control of neonatal sepsis using meta-analysis.

Methods

The China National Knowledge Infrastructure, WanFang Data, China Biological Medicine Disc, PubMed, Embase, Cochrane Library, and Web of Science databases were electronically searched to collect studies on the association between the MBL gene variants and the risk of neonatal sepsis. Original articles from case-control and cohort studies on the relationship between MBL polymorphisms and neonatal sepsis were considered eligible. Meta-analysis was performed using Stata 15.0 software. The chi-square-based Q test and I² statistics were used to assess heterogeneity.

SUBMITTER: Ma J 

PROVIDER: S-EPMC10112022 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature