A study on genetic and mutans streptococcal transmissibility of dental caries.

ABSTRACT:

Background

Dental caries is characterized by an interplay between environmental and genetic factors.

Aim

The aim of this study was to analyse the transmissibilities of high caries risk chromosomal loci at 5q 12.1-13.3 and low caries risk chromosomal loci at 13q31.1 and Streptococcus mutans (S. mutans) in family units.

Materials

This prospective cohort study was performed on 56 families grouped into four: (a) Group I: 18 families of children with caries affected primary teeth; (b) Group II: 21 families of children with caries in permanent teeth; (c) Group III: 6 families of children with no caries in primary teeth and (d) Group IV: 12 families of children with no caries in permanent teeth. Blood, saliva and plaque samples were collected from consenting study participan

SUBMITTER: Chatterjee S 

PROVIDER: S-EPMC10112085 | biostudies-literature | 2022 Oct-Dec

REPOSITORIES: biostudies-literature