Research article network analysis of polymicrobial chronic wound infections in Masanga, Sierra Leone.

ABSTRACT:

Background

Chronic wounds are frequently colonized or infected with multiple bacterial or fungal species, which can both promote or inhibit each other. Network analyses are helpful to understand the interplay of these species in polymicrobial infections. Our aim was to analyse the network of bacterial and fungal species in chronic wounds.

Methods

Swabs (n = 163) from chronic wound infections (Masanga, Sierra Leone, 2019-2020) were screened for bacterial and fungal species using non-selective agars. Some of these wounds were suspected but not confirmed Buruli ulcer. Species identification was done with MALDI-TOF mass spectrometry. Network analysis was performed to investigate co-occurrence of different species within one patient. All species with n ≥ 10 isolates were taken in

SUBMITTER: Sandmann S 

PROVIDER: S-EPMC10112320 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature