Roads Diverged: Developmental Trajectories of Irritability From Toddlerhood Through Adolescence.

ABSTRACT:

Objective

Irritability is a dimensional trait that manifests from early life and is a robust transdiagnostic risk factor for psychopathology and impairment. A large, national dataset was leveraged to identify and broadly characterize trajectories from toddlerhood through adolescence, which is crucial for timely, targeted interventions.

Method

Data on irritability and a broad array of potential factors affecting irritability development from 4,462 children assessed longitudinally at ages 3, 5, 9, and 15 were included. Latent class growth models identified groups of children based on their nonlinear irritability trajectories from toddlerhood to adolescence. LASSO regression then identified key characteristics differentiating trajectory groups.

Results

Five distinct irri

SUBMITTER: Yu Q 

PROVIDER: S-EPMC10112490 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature