Combined QTL mapping on bi-parental immortalized heterozygous populations to detect the genetic architecture on heterosis.

ABSTRACT: From bi-parental pure-inbred lines (PIL), immortalized backcross (i.e., IB₁ and IB₂, representing the two directions of backcrossing) and F₂ (i.e., IF₂) populations can be developed. These populations are suitable for genetic studies on heterosis, due to the present of both homozygous and heterozygous genotypes, and in the meantime allow repeated phenotyping trials across multiple locations and years. In this study, we developed a combined approach of quantitative trait locus (QTL) mapping, when some or all of the four immortalized populations (i.e., PIL, IB₁, IB₂, and IF₂) are available. To estimate the additive and dominant effects simultaneously and accurately, suitable transformations are made on phenotypic va

SUBMITTER: Huo X 

PROVIDER: S-EPMC10112513 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature