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Safety and effectiveness of vaccines against COVID-19 in children aged 5-11 years: a systematic review and meta-analysis.


ABSTRACT:

SUBMITTER: Piechotta V 

PROVIDER: S-EPMC10112865 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature

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Safety and effectiveness of vaccines against COVID-19 in children aged 5-11 years: a systematic review and meta-analysis.

Piechotta Vanessa V   Siemens Waldemar W   Thielemann Iris I   Toews Markus M   Koch Judith J   Vygen-Bonnet Sabine S   Kothari Kavita K   Grummich Kathrin K   Braun Cordula C   Kapp Philipp P   Labonté Valérie V   Wichmann Ole O   Meerpohl Joerg J JJ   Harder Thomas T  

The Lancet. Child & adolescent health 20230418 6


<h4>Background</h4>To date, more than 761 million confirmed SARS-CoV-2 infections have been recorded globally, and more than half of all children are estimated to be seropositive. Despite high SARS-CoV-2 infection incidences, the rate of severe COVID-19 in children is low. We aimed to assess the safety and efficacy or effectiveness of COVID-19 vaccines approved in the EU for children aged 5-11 years.<h4>Methods</h4>In this systematic review and meta-analysis, we included studies of any design id  ...[more]

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