A snapshot of lung cancer: where are we now?-a narrative review.

ABSTRACT:

Background and objective

The global impact of cancer and cancer-related deaths has been a huge challenge and continues to be a setback in the health sector and beyond even in recent times. Cancer is the second leading cause of death globally with lung cancer (LC) being the second most prevalent malignancy and the leading cause of mortality amongst cancers in men and women worldwide. LC still constitutes a major burden despite recent advances in diagnostic and treatment tools. In this article, we review the trends in LC with an emphasis on non-small cell LC. We aimed to identify nuclear and mitochondrial genetic alterations, microbiome dysbiosis, and their significance in non-small cell LC tumorigenesis as well as its relevance in the future management of LCs.

Methods

We iden

SUBMITTER: Ibodeng GO 

PROVIDER: S-EPMC10113107 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature