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Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer.


ABSTRACT: Wu et al. report that patients with hematologic malignancies have reduced immunity against SARS-CoV-2 Omicron subvariants and Sotrovimab retains neutralizing capacity against all tested Omicron subvariants.

SUBMITTER: Wu MY 

PROVIDER: S-EPMC10113515 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature

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Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer.

Wu Mary Y MY   Shepherd Scott T C STC   Fendler Annika A   Carr Edward J EJ   Au Lewis L   Harvey Ruth R   Dowgier Giulia G   Hobbs Agnieszka A   Herman Lou S LS   Ragno Martina M   Adams Lorin L   Schmitt Andreas M AM   Tippu Zayd Z   Shum Benjamin B   Farag Sheima S   Rogiers Aljosja A   O'Reilly Nicola N   Bawumia Philip P   Smith Callie C   Carlyle Eleanor E   Edmonds Kim K   Del Rosario Lyra L   Lingard Karla K   Mangwende Mary M   Holt Lucy L   Ahmod Hamid H   Korteweg Justine J   Foley Tara T   Barber Taja T   Hepworth Stephanie S   Emslie-Henry Andrea A   Caulfield-Lynch Niamh N   Byrne Fiona F   Deng Daqi D   Williams Bryan B   Brown Michael M   Caidan Simon S   Gavrielides Mike M   MacRae James I JI   Kelly Gavin G   Peat Kema K   Kelly Denise D   Murra Aida A   Kelly Kayleigh K   O'Flaherty Molly M   Popat Sanjay S   Yousaf Nadia N   Jhanji Shaman S   Tatham Kate K   Cunningham David D   Van As Nicholas N   Young Kate K   Furness Andrew J S AJS   Pickering Lisa L   Beale Rupert R   Swanton Charles C   Gandhi Sonia S   Gamblin Steve S   Bauer David L V DLV   Kassiotis George G   Howell Michael M   Walker Susanna S   Nicholson Emma E   Larkin James J   Wall Emma C EC   Turajlic Samra S  

Cancer cell 20230413 5


Wu et al. report that patients with hematologic malignancies have reduced immunity against SARS-CoV-2 Omicron subvariants and Sotrovimab retains neutralizing capacity against all tested Omicron subvariants. ...[more]

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