Joint association of hyperuricemia and chronic kidney disease with mortality in patients with chronic heart failure.

ABSTRACT:

Background

The joint association of hyperuricemia and chronic kidney disease (CKD) with mortality in patients with chronic heart failure (CHF) is not conclusive.

Methods

This retrospective cohort study was conducted in Chinese People's Liberation Army General Hospital, Beijing, China. We included 9,367 patients with CHF, who were hospitalized between January 2011 and June 2019. The definitions of hyperuricemia and CKD were based on laboratory test, medication use, and medical record. We categorized patients with CHF into 4 groups according to the absence (-) or presence (+) of hyperuricemia and CKD. The primary outcomes included in-hospital mortality and long-term mortality. We used multivariate logistic regression and Cox proportional hazards regression to estimate the mort

SUBMITTER: Wang C 

PROVIDER: S-EPMC10113528 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature